Abstract. Streptomyes plays a role in the degradation process of organic compounds that existed on the soil, especially in the mangrove area through several enzyme activities. These bacteria can help in providing organic ingredients as a food source for organisms that live around mangroves including the nipah worms (Namalycastis rhodochorde). This study aims to determine the enzyme activity profile of seven actinomycetes culture that have been isolated from mangrove soil in Sungai Kakap district, West Kalimantan. Determining of enzymatic activity was carried out on agar base which was added with starch, milk casein, cellulose and gelatine. Catalase activity was conducted using 3% of H²O² solution. The results showed that six Streptomyes spp. had proteolytic, cellulolytic, amylolytic, gelatin liquefaction, and catalase activities. Streptomyes NrASA1 has the highest proteolytic activity index values, namely 0.57. Streptomyes NrASA3 and Streptomyes NrASA4 has the highest amylolytic and cellulolytic activity index values, respectively 0.76 and 1.15. The enzymatic activity profile of indigenous Streptomyes spp. can be utilized for the development of feed formulas for nipah worm.