The SEA+ Conference on Biodiversity and Biotechnology 2018

The Utilization of Seaweeds as an Inexpensive Source of New Drug Agent

Bertoka Fajar Surya Perwira Negara (1) , Oktoviani Oktoviani (2) , Enny Nugraheni (3) , Aradea Bujana Kusuma (4) , Resti Kontesa (5) , Efrodika D Putra (6) , Dianty Siallagan (7) , Nurlaila Ervina Herliany (8) , Dewi Purnama (9)


(1) Universitas Bengkulu
(2) Department of Chemistry, University of Bengkulu, Indonesia
(3) Faculty of Medical, University of Bengkulu, Indonesia
(4) Department of Marine Science, University of Bengkulu, Indonesia
(5) Department of Marine Science, University of Bengkulu, Indonesia
(6) Department of Marine Science, University of Bengkulu, Indonesia
(7) Department of Marine Science, University of Bengkulu, Indonesia
(8) Department of Marine Science, University of Bengkulu, Indonesia
(9) Department of Marine Science, University of Bengkulu, Indonesia

Building: Java Heritage Convention
Room: Room II
Date: 2018-11-07 11:45 – 12:00
Last modified: 2019-05-10

Abstract


The increasing of human population have same trend in the rate of infection by pathogenic bacterial. The uses of synthetic antibacterial chemicals continuously have a negative effect. The pathogenic bacterial will be resistance in high doses. Alternatively, the discovery of new antibacterial agent is urgent need. The searching of new drugs agent as antibacterial have been looking from marine organisms, especially seaweeds. The aims of this research were to measure the clear zone of seaweeds against bacterial test and to evaluated the ability of seaweed as antibacterial agent. The samples of seaweeds were collected from Pantai Panjang, Bengkulu, Indonesia using purposive sampling method. Maceration method used in this research to extract the antibacterial agent from seaweeds. Agar diffusion method was used as antibacterial activity assay against Escherichia coli, Salmonella typhii and Staphylococcus aureus as bacterial test. Totally, there are three species of seaweeds that found in the location e.g Halimeda discoidea, Halimeda micronesica, and Caulerpa taxifolia. The antibacterial assay presented H. discoidea and C. taxifolia have the antibacterial activity against all bacterial test with clear zone that categorized into moderate and high. Meanwhile, H. micronesica have the potential as antibacterial agent against E. coli and S. typhii with clear zone that categorized into moderate and high. In the future, it could be a potential new drugs agent especially for antibacterial agent.

 

 

Bertoka Fajar Surya Perwira Negara

Oktoviani Oktoviani
Enny Nugraheni
Aradea Bujana Kusuma
Resti Kontesa
Efrodika D Putra
Dianty Siallagan
Nurlaila Ervina Herliany
Dewi Purnama


Keywords


antibacterial; clear zone; drugs; resistance; seaweeds